Utrogestan Capsules (Oral)

Side effects that may happen with this medicine

Common (may affect up to 1 in 10 people)

• Weight changes
• Insomnia (difficulty falling and staying asleep, poor quality of sleep)
• Feeling tired or dizzy (see also section “Driving and using machines”)
• Headaches
• Abdominal swelling or pain
• Feeling sick (nausea)
• Itching
• Irregular or intermenstrual bleeding
• Vaginal bleeding
• Breast pain or tenderness
• Missing or absent periods
• Tiredness
• Feeling generally unwell

Uncommon (may affect up to 1 in 100 people)

• Problems due to the formation of blood clots in the blood vessels (thromboembolic disorders)
• Fluid retention
• Feeling agitated or anxious
• Lack of interest or energy
• Depression
• Disorientation
• Mood swings
• Nervousness
• Memory loss
• Migraine
• Sensations like numbness, tingling, pins and needles
• Speech disorder
• Fainting
• Changes in your vision
• Ringing or buzzing in the ears
• A spinning sensation
• Palpitations or rapid heartbeat
• Hot flush
• Low blood pressure
• Difficulty breathing
• Being sick (vomiting)
• Diarrhoea
• Constipation
• Non-severe and reversible liver disorders
• Yellowing of the skin or the whites of your eyes (jaundice)
• Acne
• Hair loss
• Reddening of the skin
• Excessive sweating
• Itchy skin or rash
• Joint, back or muscle pain
• Muscle spasms
• Abnormal menstrual cycle
• Breast discomfort
• Irregular thickening of the uterine lining (endometrial hyperplasia)
• Vaginal discharge
• A burning pain or discomfort in the vulva
• Breast tenderness
• Excessive hair (where there is usually very little or no hair)
• Weakness
• Chest discomfort or pain
• Swelling

Rare (may affect up to 1 in 1,000 people)

• Change in glucose tolerance
• Change in libido
• Eye irritation
• Loss of appetite
• Painful urination

Very rare (may affect up to 1 in 10,000 people)

• Tan or dark skin discolouration (so-called mask of pregnancy)
• Allergic reactions

Not known (frequency cannot be estimated from the available data)

• Infection of the parts of the body that collect and pass out urine (urinary tract infection)
• An inflammation of the vagina that can result in discharge, itching and pain (vaginitis)
• Taste disturbance
• Period pains
• Unexpected vaginal bleeding, spotting or blood-streaked discharge
• Fever

Side effects reported with other HRTs

• Gall bladder disease
• Various skin disorders
  • Discolouration of the skin, especially of the face or neck, known as “pregnancy patches” (chloasma)
  • Painful reddish skin nodules (erythema nodosum)
  • Rash with target-shaped reddening or sores (erythema multiforme)
• Breast pain (mastodynia)
• Fluid retention (oedema)
• Weight changes
• Increase or decrease in sexual desire
• Depression
• Rashes
• Urticaria (itchy, lumpy rash)
• Patchy brown or dark brown skin discolouration (melasma)
• Fever
• Insomnia (inability to obtain an adequate amount or quality of sleep)
• Alopecia (hair loss)
• Irregular menstruation
• Lack of menstrual periods