Premique Low Dose Tablets

Premique is a hormonal drug used as part of hormonal therapies in women. There are two active ingredients in Premique:

• Estradiol (an estrogen hormone) this helps to reduce menopausal symptoms 

• Medroxyprogesterone (a progestin hormone) 

Premique refreshes the hormonal balance in the body and reduces menopausal symptoms such as: 

• Night sweats

• Insomnia 

• Hot flushes 

• Loss of libido 

• Pain during sexual intercourse 

• Dry mucous membranes (eys, vagina, mouth)

• Osteoporosis

• Anxiety, irritability, depression 

The benefits of Premique are, helping to reduce the symptoms of menopause and for women who have not had a hysterectomy, increased estrogen levels can stimulate the growth of the uterine lining, which can cause uterine cancer. The inclusion of progesterone is done to counteract the effects of estrogen on the uterine lining, which reduces the risk of cancer.

All medicines can cause side effects. Although not everybody gets them. 

The following side effects may occur with this medicine:

Very common (may affect more than 1 in 10 patients):

• Chest Pain 

• Bleeding or spotting 

• Depression

• Nipple discharge 

• Tenderness or pain in the breasts

Please see the patient information leaflet for more side effects and information about Premique Low Dose.

Reporting of side effects

If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in the above description and patient information leaflet. You can also report side effects directly via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard or search for “MHRA yellowcard” in the Google Play or Apple App Store. By reporting side effects you can help provide more information on the safety of this medicine.