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Simbrinza contains the active ingredient Brimonidine which belongs to a class of medications called alpha-adrenergic agonists and Brinzolamide which is an carbonic anhydrase inhibitor.
These eye drops are used to decrease pressure in the eyes of patients with glaucoma and ocular hypertension.
Brimonidine works by reducing the amount of fluid that you make in the front part of your eye (called aqueous humour) and by increasing the drainage of fluid from your eye. As a result pressure is lowered within your eye.
Brinzolamide is an carbonic anhydrase inhibitor. It works by blocking the action of an enzyme in the body which is called carbonic anhydrase. Carbonic anhydrase is usually responsible for the production of a salt called bicarbonate in the body. Bicarbonate is needed for the production of the aqueous humour. A decrease in the production of bicarbonate, in turn decreases the production of aqueous humour.
Simbrinza is a prescription only medicine and an Emergency Supply can only be issued if you are currently being prescribed this medication by your GP for high blood pressure. You will need to fill out a questionnaire, which is then reviewed to make sure Simbrinza is a suitable treatment for you. If your order is approved, your Simbrinza can be sent directly to you.
Always take this medication exactly as directed by your GP.
Keep out of sight and Reach of children.
If you are taking or using any new medications even over the counter medicines whilst using Simbrinza you should make your GP aware to prevent interactions.
Active ingredients: Brimonidine
Simbrinza must be used exactly as your doctor or pharmacist has told you. If you are unsure contact your GP.
Recommended starting dose is usually:
ONE drop in the affected eye or eyes twice a day (Ideally at the same time each day)
Itchy, irritated, red, stinging or burning eyes
Dry eyes
Watering or discharge from the eyes
Redness or swelling of the eyelids
Light sensitivity
Blurry vision
Headache
Drowsiness
Difficulty falling asleep or staying asleep
Dry mouth
Runny nose and other cold symptoms
Cough
Sore throat
Flu-like symptoms
Pain or feeling of pressure on the face
Heartburn
Any concerns or queries regarding any side effects this medicine has caused or could cause you can call your GP or our pharmacist.
If you have any severe side effects seek medical assitance as soon as possible.
If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in the above description and patient information leaflet. You can also report side effects directly via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard or search for “MHRA yellowcard” in the Google Play or Apple App Store. By reporting side effects you can help provide more information on the safety of this medicine.
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