Like all medicines, Prochlorperazine Tablets can cause side effects, although not everybody gets them.
Serious side effects
If you experience any of the following side effects, you should stop taking Prochlorperazine Tablets and contact your doctor immediately:
- Symptoms of an allergic reaction such as rash and swelling of the face, tongue or throat.
- A high temperature, pale complexion, muscle stiffness and changes in levels of alertness, you may have developed a serious condition called neuroleptic malignant syndrome.
- Convulsions (fits).
- Signs of infection such as shivering, headache, sweating, high temperature, flushing, a sore throat or mouth and swollen glands.
- Very fast, uneven or forceful heartbeats (palpitations) and breathing problems such as wheezing, shortness of breath, tightness in the chest and chest pain.
- Blood clots in the veins especially in the legs (symptoms include swelling, pain and redness in the leg), which may travel through blood vessels to the lungs causing chest pain and difficulty in breathing.
- Symptoms of decreased sodium concentration in the blood, such as nausea and vomiting, headache, confusion, loss of energy, restlessness, muscle weakness, spasms or cramps, seizures and coma.
- In elderly people with dementia, a small increase in the number of deaths has been reported for patients taking medicines of the same type as Prochlorperazine Tablets compared with those not taking these medicines.
Other side effects include:
Rare: may affect up to 1 in 1,000 people
Very rare: may affect up to 1 in 10,000 people
- breast swelling (in men as well as in women)
- milk secretion from the breasts which is not due to breast-feeding
- absence of menstrual periods
Unknown: frequency cannot be estimated from the available data
- drowsiness
- dizziness
- dry mouth
- inability to sleep (insomnia)
- agitation
- a feeling of restlessness or anxiety that can range from mild to severe
- skin reactions
- increased sensitivity to sunlight
- low blood pressure (this makes you feel dizzy or faint, particularly when you stand up), particularly in elderly or volume depleted patients (those who have lost both water and salts from the body).
- high blood sugar level, which can cause increased thirst, a dry mouth, needing to urinate frequently, tiredness and recurrent infections such as thrush
- a condition known as cholestasis where bile cannot flow properly in the body, and can cause itchiness, jaundice (yellowing of the skin and/or the whites of the eyes), pale stools and dark urine
- abnormal movements, tremors and muscle rigidity, and unusual movements of the face and tongue
- impotence, ejaculation problems and persistent/ painful erections
- local irritation to the gum and mouth
- numbness of mouth
- tingling, pricking or burning of mouth
- altered or decreased ability to taste
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