Aklief cream (Trifarotene)

What is Aklief Cream?

Aklief is part of a group of medications called retinoids, as it contains the active ingredient Trifarotene. It's used to treat non-inflammatory and inflammatory acne by promoting faster skin cell turnover, helping to unclog pores and reducing acne. 

How does Aklief Cream Work?

Aklief cream works using the active ingredient, Trifarotene, which is a chemical that aids the skin in replacing dead skin cells at a faster rate than usual, exfoliating the old cells. This helps to prevent acne from returning. It also decreases swelling and inflammation of the skin, helping to reduce redness. 

Aklief cream helps to keep follicles clear and prevents buildup of dead skin cells, meaning less formation of whiteheads and blackheads. 

Aklief cream is used to treat acne of the face, neck, chest, back and shoulders. 

Key Benefits

• Paraben Free
• Contains a known skin conditioning agent and protectant called Allantoin 
• Non greasy 
• Not sensitive to pH changes
• Hydrate and improve skin softness, flexibility and smoothness 
• Aklief can be used along with an oral or topical antibiotic treatment 
• Results may be seen within 2 weeks

Can I use a moisturiser with Aklief Cream?

Yes, it is recommended to use a moisturiser as part of your daily skin routine. 

Step 1 - Use a gentle and mild cleanser such as Cetaphil Gentle Skin Cleanser to clear your face of dirt and grime first. 

Step 2 - Once the skin is dry, apply a thin layer of Aklief Cream once daily in the evening. One pump for the face, two pumps for the chest, shoulders and back.

Step 3 - Use a gentle moisturiser such as Cetaphil Moisturising Lotion as often as needed to help minimise skin dryness and irritation. 

Step 4 - Use a sunscreen that's SPF15 or higher and wear protective clothing. Always use sunscreen when using Aklief Cream.

Can Aklief Cause Irritation?

Yes, common side effects include itching, application site irritation and sunburn. You can also experience scaling, dryness and stinging and burning. Using a moisturiser from the onset of treatment can help minimise these reactions. If irritation continues, discontinue use. 

You can download a copy of how to apply, along with precautions and information from the Aklief website here. 

How to use Aklief Cream.

1. First, prime the pump by pressing down several times until a small amount of cream is produced (up to 10 times maximum).
2. Clean and dry skin, and apply only a thin layer of cream to the affected areas in the evening.
3. For the face (forehead, cheeks, nose, and chin), one pump should be enough.
4. For the upper trunk (upper back, shoulders, and chest), two pumps should be enough. If acne is present on the middle and lower back, an additional pump can be used.
5. Using more than four pump actuations in a day is not recommended.

Avoid contact with eyes, eyelids, lips and inside the nose or mouth. If the cream accidentally comes into contact with these areas, wash them with lukewarm water straight away.

You must always wash your hands straight after applying the cream.

If you need to use a moisturiser during the Aklief treatment, it can be applied before or after Aklief, ensuring time for the skin to dry between applications so the cream can soak in.

Your doctor will decide how long you should use Aklief Cream for. After three months of treatment, your doctor may want to check the progress of your acne.

Common side effects:

• Itching
• Burning
• Skin irritation at the application site.

Uncommon side effects:

• Redness
• skin allergy
• Rash
• Dry skin
• Skin loss
• Discoloration
• Swelling
• Skin pain

If you experience any of the Aklief cream side effects or any side effects not listed above. Please do not hesitate to contact us for advice.

Reporting of side effects

If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in the above description and patient information leaflet. You can also report side effects directly via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard or search for “MHRA yellowcard” in the Google Play or Apple App Store. By reporting side effects you can help provide more information on the safety of this medicine.